王一倩
发布时间:2021-11-29

 

王一倩:女中共党员

电话:020-83079001 email: yiqian.wang@gzhmu.edu.cn

广州医科大学生命科学学院生化教研室讲师,博士

教育经历

2009.09-2013.06 惠州学院 学士

2011.08-2013.05 美国内布拉斯加大学奥马哈分校,学士 

2013.07-2019.05 美国内部拉斯加大学医学中心,博士

 

工作经历

2019.08-至今 广州医科大学 讲师

 

教学经历及成果

教授本科生课程《生物化学与分子生物学》;研究生课程《分子生物学实验理论与技术

 

研究方向:急性髓系白血病发展机制以及耐药机制

 

主持项目

1. 广州市科技局探究白血病细胞中IL-33激活p38 MAPK通路对抑制细胞凋亡的作用机制2021.04-2023.03,主持。

2. 广东省教育厅青年创新人才项目,2019KQNCX114IL1RL1/IL-33信号通路在急性髓系白血病发展中的机制研究,2020.05-2022.04,主持。

3. 广州医科大学大学生实验室开放项目,探究白介素IL-33抑制白血病细胞凋亡的作用机制,2020.07-2022.06,主持。

 

发表文章(部分)

1. Yiqian Wang#, Haibo Su#, Muxia Yan#, Li Zhang, Jiancheng Tang, Quanxin Li, Xiaoqiong Gu*, and Qing Gong*. Interleukin-33 Promotes Cell Survival via p38 MAPK-Mediated Interleukin-6 Gene Expression and Release in Pediatric AML. Front Immunol. 2020;11:595053.

2. Yiqian Wang, Ying Xie, Jacob Williams, Yu Hang, Lisa Richter, Michelle Becker, Catalina Amador, David Oupický, R Katherine Hyde*. Use of polymeric CXCR4 inhibitors as siRNA delivery vehicles for the treatment of acute myeloid leukemia. Cancer Gene Ther. 2019; 27(1-2): 45-55.

3. Yiqian Wang, Lisa Richter, Michelle Becker, Catalina Amador, R Katherine Hyde*. IL1RL1 is dynamically expressed on Cbfb-MYH11(+) leukemia stem cells and promotes cell survival. Sci Rep. 2019; 9 (1): 1729.

4. Lisa Richter#, Yiqian Wang#, R Katherine Hyde*. Targeting binding partners of the CBFβ-SMMHC fusion protein for the treatment of inversion 16 acute myeloid leukemia. Oncotarget. 2016; 7(40): 66255-66266.

5. Yiqian Wang#, Hanyi Hou#, Zhongping Liang#, Xuexin Chen, Xindan Lian, Jie Yang, Zeyu Zhu, Huanmin Luo, Haibo Su*, &Qing Gong*. 2021. P38 MAPK/AKT signalling is involved in IL-33-mediated anti-apoptosis in childhood acute lymphoblastic leukaemia blast cells. Ann Med 53:1461-1469. 

6. Yiqian Wang, Huanmin Luo., Mengyi Wei., Michelle Becker., R Katherine Hyde, & Qing Gong*.  2020. IL-33/IL1RL1 axis regulates cell survival through the p38 MAPK pathway in acute myeloid leukemia. Leuk Res 96:106409.

7. Muxia Yan., Ying Wu, Jianjun Xia, Xiaohong Zhang, & Yiqian Wang*. 2021. Cytologic diagnosis of metastatic embryonal rhabdomyosarcoma in cerebrospinal fluid: A case report. Diagn Cytopathol 49:E320-e324.