邓秋狄，暨南大学生物化学与分子生物学博士，硕士研究生导师。主要研究方向为小分子生物化学、分子药理学；聚焦于寻找和发现血管新生性疾病（类风湿关节炎、肿瘤）有效的药物靶点，致力于发展和应用新颖的生物活性小分子。

联系邮箱：dengqiudi@gzhmu.edu.cn

研究方向：小分子生物化学、分子药理学

主要科研项目：

1. 国家自然科学基金青年科学基金项目；基于周细胞功能探究过山枫活性成分抗类风湿关节炎滑膜血管新生的作用；2022.01-2024.12，主持。

2. 广州市科学技术局基础与应用基础研究项目；AXL经由TGF-β1调控肿瘤相关巨噬细胞的极化促进非小细胞肺癌转移的作用研究；2021.04-2023.03，主持。

3. 广东省中医药局科研项目；过山枫活性成分扁蒴藤素靶向MAGL抑制类风湿关节炎滑膜血管新生的作用及机制研究；2021.01-2022.12，主持。

4. 广州市教育局高校科研项目；AXL介导的肿瘤相关巨噬细胞极化促进非小细胞肺癌转移的作用与机制研究；2021.01-2022.12，主持。

代表性论文：

1. Deng Qiudi^#; Lei Xueping^#; Zhong Yihang; Chen Minshan; Ke Yuanyu; Li Zhan; Chen Jing; Huang Lijuan; Zhang Yu; Liang Lu; Lin Zhongxiao; Liu Qing*; Li Songpei*; Yu Xiyong*. Triptolide suppresses the growth and metastasis of non-small cell lung cancer by inhibiting β-catenin-mediated epithelial- mesenchymal transition. Acta Pharmacologica Sinica, 2021, 42(9): 1486-1497.

2. Lei Xueping^#; Zhong Yihang^#; Huang Lijuan; Li Songpei; Fu Jijun; Zhang Lingmin; Zhang Yu; Deng Qiudi^*; Yu Xiyong^*. Identification of a novel tumor angiogenesis inhibitor targeting Shh/Gli1 signaling pathway in Non-small cell lung cancer. Cell Death & Disease, 2020, 11(4): 232.

3. Deng Qiudi^#; Liu Yujun^#; Li Xin^#; Yan Bin^#; Sun Xu^#; Tang Wei; Trang Phong; Yang Zhu; Gong Hao; Wang Yu; Lu Jie; Chen Jun; Xia Chuan; Xing Xiwen^*; Lu Sangmei^*; Liu Fenyong^*. Inhibition of human cytomegalovirus major capsid protein expression and replication by ribonuclease P-associated external guide sequences. RNA, 2019, 25(5): 645-655.

4. Deng Qiudi^#; Chen Zisheng^#; Shi Lei; Lin Huafeng^*. Developmental progress of CRISPR/Cas9 and its therapeutic applications for HIV-1 infection. Reviews in Medical Virology, 2018, 28(5): e1998.

5. Deng Qiudi; Bai Shutong; Gao Wanjiao; Tong Li^*. Pristimerin inhibits angiogenesis in adjuvant-induced arthritic rats by suppressing VEGFR2 signaling pathways. International Immunopharmacology, 2015, 29(2): 302-313.

6. Lin Kaili^#; Zhang Zhang^#; Zhang Zhu^#; Zhu Peili; Jiang Xiaoli; Wang Ying; Deng Qiudi^*; Yung Ken Kin Lam^*; Zhang Shiqing^*. Oleanolic Acid Alleviates Cerebral Ischemia/Reperfusion Injury via Regulation of the GSK-3β/HO-1 Signaling Pathway. Pharmaceuticals, 2022, 15(1): 1.

7. Peng Qingsheng^#; Li Hua^#; Deng Qiudi^#; Liang Lu; Wang Fei; Lin Yinshan; Yang Langyu; Zhang Yu*; Yu Xiyong*; Zhang Lingmin*. Hybrid artificial cell-mediated epigenetic inhibition in metastatic lung cancer. Journal of Colloid and Interface Science, 2021, 603: 319-332.