宋玉龙，男，中共党员。

办公电话：156xxxx7362，email: songyulong99@126.com

广州医科大学生命科学学院，“南山学者”骨干人才。

 

教育经历

2005.09-2009.06 郑州大学 学士

2009.09-2012.06 温州医科大学 硕士

2012.09-2016.01 中国科学院大学&中国科学院水生生物研究所 博士

 

工作经历

2016.03-2022.06 中山大学 特聘副研究员

2022.06-至今 广州医科大学 南山学者

 

教学经历及成果

研究生课程《组学技术与应用》

 

教学成果

1. 国际基因工程机器大赛（iGEM），金奖，2020年，生物信息指导教师

 

研究方向：

开发新的高通量测序技术及生物信息学分析方法，从而探索RNA修饰（特别是A-to-I RNA编辑）和RNA结合蛋白（简称RBP，特别是ADAR蛋白家族）的分布规律、功能及作用机制，特别是其在人类重大疾病发生和治疗中的作用机制及应用。

 

主持项目

1. 国家重点研发计划青年科学家项目，“干细胞研究与器官修复”专项；2021YFA1102500，mRNA可变剪切调控重编程心肌异质性的分子机制及应用研究，2021.12-2026.06，100万，项目骨干；

2. 国家自然科学基金委员会，青年项目；31900437，基于irCLASH方法构建人类ADAR蛋白家族的体内双链RNA底物图谱，2020.01-2022.12，24万元，在研，主持；

3. 教育部，中央高校基本科研业务费-青年教师培育项目；19lgpy180，调控人类RNA 上A-to-I编辑水平的非编码RNA的作用机制研究，2019.01-2021.12，15.33万元，结题，主持。

 

发表文章（部分）

1. Yulong Song#*, Xiuju He#, Wenbing Yang#, Yaoxing Wu, Jun Cui, Tian Tang, Rui Zhang*;Virus-specific editing identification approach reveals the landscape of A-to-I editing and its impacts on SARS-CoV-2 characteristics and evolution; Nucleic Acids Research;50(5):2509-2521 (2022).

2. Yulong Song#, Wenbing Yang#, Qiang Fu, Liang Wu, Xueni Zhao, Yusen Zhang and Rui Zhang*; irCLASH reveals RNA substrates recognized by human ADARs; Nature Structural & Molecular Biology;27(4):351–362 (2020).

3. Yulong Song#, Lishi Li#, Wenbing Yang, Qiang Fu, Wanying Chen, Zeng Fang, Wen Li*, Nannan Gu*, Rui Zhang*;Sense-antisense miRNA pairs constitute an elaborate reciprocal regulatory circuit;Genome Research;30(5): 661-672 (2020).

4. Lishi Li#, Yulong Song#, Xinrui Shi, Jianheng Liu, Shaolei Xiong, Wanying Chen, Qiang Fu, Zichao Huang, Nannan Gu*, and Rui Zhang*;The landscape of miRNA editing in animals and its impact on miRNA biogenesis and targeting;Genome Research;28(1):132-143 (2018).

5. Liang Zhao, Yulong Song, Lin Li, Nanqin Gan, Jerry J. Brand, Lirong Song;The highly heterogeneous methylated genomes and diverse restriction-modification systems of bloom-forming Microcystis;Harmful Algae;2018, 75(87-93).

6. Qin Tang, Yulong Song, Mijuan Shi, Yingyin Cheng, Wanting Zhang, Xiao-Qin Xia;Inferring the hosts of coronavirus using dual statistical models based on nucleotide composition;Scientific Reports;2015, 5(17155).

7. Nan Wu,Yu-Long Song, Bei Wang, Xiang-Yang Zhang, Xu-Jie Zhang, Ya-Li Wang, Ying-Yin Cheng, Dan-Dan Chen, Xiao-Qin Xia, Yi-Shan Lu, Yong-An Zhang. Fish gut-liver immunity during homeostasis or inflammation revealed by integrative transcriptome and proteome studies;Scientific Reports;2016, 6(36048).

8. Dianzhen Yu, Ming Xia, Liping Zhang, Yulong Song, You Duan, Tong Yuan, Minjie Yao, Liyou Wu, Chunyuan Tian, Zhenbin Wu, Xiangzhen Li, Jizhong Zhou, Dongru Qiu; RpoN (σ54) Is Required for Floc Formation but Not for Extracellular Polysaccharide Biosynthesis in a Floc-Forming Aquincola tertiaricarbonis Strain;Appl Environ Microbiol;2017, 83(14).

9. Weixing An, Feng Guo, Yulong Song, Na Gao, Shijie Bai, Jingcheng Dai, Hehong Wei, Liping Zhang, Dianzhen Yu, Ming Xia, Chunyuan Tian, Haofeng Chen, Zhenbin Wu, Tong Zhang, Dongru Qiu;Comparative genomics analyses on EPS biosynthesis genes required for floc formation of Zoogloea resiniphila and other activated sludge bacteria;Water Res.;2016, 1(102): 494-504.

10. Nu Zhang, Xu-Jie Zhang, Yu-Long Song, Xiao-Bing Lu, Dan-Dan Chen, Xiao-Qin Xia, Yong-An Zhang;Preferential combination between the light and heavy chain isotypes of fish immunoglobulins;Developmental and Comparative Immunology;2016, 61: 169-179.

11. Linsheng Yu, Jipu Yi, Guanghua Ye, Yuanyuan Zheng, Zhijian Song, Yulong Song, Yanmei Yang and Qiyu Bao;Effects of curcumin on levels of nitric oxide synthase and AQP-4 in a rat model of hypoxia-ischemic brain damage;Brain research;2012, 1475: 88-95.

12. Teng Xu, Jingxian Fei, Yulong Song, Jun Ying, Zhijian Song, Yunling Qi,  Xiaoding Yao, Peizhen Li, Huiguang Yi, Tieli Zhou, Yuxin Niu, Zuyuan Xu, Shouguang Jin and Qiyu Bao;Identification and characterization of two novel blaKLUC group members through large scale multidrug resistance plasmids sequencing;PloS one;2012, 7(10): e47197.

13. Peizhen Li, Biaobang Chen, Zhijian Song, Yulong Song, Yanmei Yang, Ping Ma, Jianting Li, Jun Ying, Huili Wang, Li Ding, Shouguang Jin, Qiyu Bao, Hongjiang Yang;Bioinformatic Analysis of the Acinetobacter baumannii Phage AB1 Genome;Gene;2012, 507(2): 125-134.

14. Jimei Du, Chun Chen, Baixing Ding, Jingjing Tu, Zhiqiang Qin, Chris Parsons, Cassandra Salgado, qiangjun Cai, Yulong Song, Qiyu Bao, Liming Zhang, Jingye Pan, Liangxing Wang, Fangyou Yu;Molecular Characterization and antimicrobial susceptibility of nasal Staphylococcus aureus isolates from a Chinese medical college campus;PloS one;2011, 6(11): e27328.

 

社会任职/学术任职

1. RNA学会会员（RNA Society）

2. 中国细胞生物学学会会员