廖静:女,中共党员。
电话:139XXXX6418,email: liaojing@gzhmu.edu.cn
广州医科大学生命科学学院,生物技术系,副教授,“南山学者”后备人才。
教育经历
2007.09—2011.06 华中师范大学 学士
2011.09—2017.06 中国科学院大学/中国科学院生物物理研究所 博士
工作经历
2017.07—2019.09 中山大学 博士后
2019.09—2022.06 中山大学附属第六医院 助理研究员
2022.07—至今 广州医科大学 副教授
教学经历及成果
教授研究生课程《细胞治疗技术前沿》等。
研究方向:
1. 肿瘤免疫微环境的调节机制及新型联合治疗策略的探索;
2. 新型治疗性抗体相关药物前体的开发及应用;
3. 肿瘤治疗新靶点及预后标志物的鉴定。
主持项目
1. 国家自然科学基金青年科学项目,31900651,肝癌组织中CD169阳性单核巨噬细胞的产生与调控机制,2020.01-2022.12,24万元,在研,主持。
2. 中国博士后科学基金面上项目,2018M643302,肝癌中CD169与CD204单核巨噬细胞的转化机制和临床意义,2018.08-2020.07,5万元,已结题,主持。
3. 广东省自然科学基金面上项目,2021A1515012620,头颈鳞癌中FAP调节免疫细胞功能的机制研究,2021.01-2023.12,10万,在研,主持。
4. 高校基本科研业务费-青年教师培育项目,20ykpy10,靶向 FAP 联合化疗治疗晚期头颈鳞癌的机制与临床意义研究,2020.01-2022.12,12万,已结题,主持。
5. 广州市科技计划项目一般项目,202201010993,PD-1抗体治疗早期头颈鳞癌的疗效与机制探究,2022.04-2024.03,5万,在研,主持。
发表文章(部分)
Ÿ 共同第一作者(#)或共同通讯作者(*)论文
1. Jing Liao#, Dan-Ni Zeng#, Jin-Zhu Li, Qiao-Min Hua, Chun-Xia Huang, Jing Xu, Chong Wu, Limin Zheng, Wei-Ping Wen*, Yan Wu*. Type I IFNs Repolarized a CD169+ Macrophage Population with Anti-tumor Potentials in Hepatocellular Carcinoma. Molecular Therapy. 2022.02, 30(2):632-643. (IF: 12.91)
2. Jing Liao, Yan Luan, Zhenhua Ren, Xiaojuan Liu, Diyuan Xue, Hairong Xu, Zhichen Sun, Kaiting Yang, Hua Peng*, Yang-Xin Fu*. Converting Lymphoma Cells into Potent Antigen-Presenting Cells for Interferon-Induced Tumor Regression. Cancer Immunology Research. 2017.07, 5(7): 560-570 (IF: 12.02)
3. Jing Liao, Dan-Ni Zeng, Jin-Zhu Li, Qiao-Min Hua, Zhiyu Xiao, Chuanchao He, Kai Mao, Ling-Yan Zhu, Yifan Chu, Wei-Ping Wen, Limin Zheng, Yan Wu. Targeting Adenosinergic Pathway Enhances the Anti-tumor Efficacy of Sorafenib in Hepatocellular Carcinoma. Hepatology International. 2020.01, 14(1):80-95 (IF: 9.029)
4. Jing Liao#, Jin-Zhu Li#, Jing Xu, Yongquan Xu, Wei-Ping Wen, Limin Zheng, Lian Li. High S100A9+ Cell Density Predicts a Poor Prognosis in Hepatocellular Carcinoma Patients after Curative Resection. Aging (Albany NY). 2021.06, 13(12):16367-16380. (IF: 5.955)
5. Chengzhou Mao#, Shi-Min Zhuang#, Zijin Xia, Zhi-Wen Xiao, Chun-Xia Huang, Wei-Ping Wen, Qiang Su, Jun Chen*, Jing Liao*. Pan-cancer Analysis of GALNTs Expression Identifies a Prognostic of GALNTs Feature in Low Grade Glioma. Journal of Leukocyte Biology. 2022.01, doi: 10.1002/JLB.5MA1221-468R (IF: 6.011)
6. Xiaoxue Chen#, Zhechong Zhou#, Chunliu Huang#, Ziliang Zhou, Sisi Kang, Zhaoxia Huang, Guanmin Jiang, Zhongsi Hong, Qiuyue Chen, Mei Yang, Suhua He, Siqi Liu, Jie Chen, Kenan Li, Xin Li, Jing Liao*, Jun Chen*, Shoudeng Chen*. Crystal structures of bat and human coronavirus ORF8 protein Ig-like domain provide insights into the diversity of immune responses. Frontiers in Immunology. 2021.12, https://doi.org/10.3389/fimmu.2021.807134. (IF: 8.786)
7. Yifan Chu#, Jing Liao#, Jinqing Li, Yongchun Wang, Xingjuan Yu, Junfeng Wang, Limin Zheng, Jing Xu*, Lian Li*. CD103+ Tumor-infiltrating Lymphocytes Predict Favorable Prognosis in Patients with Esophageal Squamous Cell Carcinoma. Journal of Cancer. 2019.08, 10(21):5234-5243 (IF: 4.478)
8. Diyuan Xue#, Benjamin Moon#, Jing Liao, Jingya Guo, Zhuangzhi Zou, Yanfei Han, Shuaishuai Cao, Yang Wang, Yang-Xin Fu*, Hua Peng*. A tumor-specific pro-IL-12 activates preexisting cytotoxic T cells to control well-established tumors. Science Immunology. 2022.01, 7(67):eabi6899. (IF: 30.63)
9. Chong Wu#, Jie Lin#, Yulan Weng, Dan-Ni Zeng, Jing Xu, Shufeng Luo, Li Xu, Mingyu Liu, Qiaomin Hua, Chao-Qun Liu, Jin-Qing Li, Jing Liao, Cheng Sun, Jian Zhou, Min-Shan Chen, Chao Liu, Zhenhong Guo, Shi-Mei Zhuang, Jin-Hua Huang, Limin Zheng. Myeloid signature reveals immune contexture and predicts the prognosis of hepatocellular carcinoma. Journal of Clinical Investigation. 2020.09, 130(9):4679-4693 (IF: 19.456)
10. Zhenhua Ren, Jingya Guo, Jing Liao, Yan Luan, Zhida Liu, Zhichen Sun, Xiaojuan Liu, Yong Liang, Hua Peng*, Yang-Xin Fu*. CTLA-4 Limits Anti-CD20-Mediated Tumor Regression. Clinical Cancer Research. 2017.01, 23(1): 193-203 (IF: 13.801)
社会任职/学术任职
1. 广东省免疫学会青年工作者委员会,委员,2020.12-2024.12。