陈冰洁
编辑:综合办公室     发布时间:2023-12-04


陈冰洁,女,中共党员。

广州医科大学南山学者第四层次骨干人才,教授

电话:134xxxx2537

邮箱: bingjiechen@gzhmu.edu.cn


教育经历

(1) 2014-09 至 2019-06, 中山大学, 生物信息学, 博士

(2) 2009-09 至 2014-06, 中山大学, 法医学, 学士


工作经历


(1) 2019-10 至 2022-09, the Institute of Cancer Research, London, UK

(2) 2022-10 至 2023-07, 广州医科大学, 生命科学学院, 讲师

(3) 2023-07至今,广州医科大学, 生命科学学院,教授



研究方向

1.群体遗传学

2.肺泡损伤修复

3.体细胞及肿瘤演化


主持项目

1. 国家自然科学基金委,青年科学基金项目, 32300492,   2024-01-01 至 2026-12-31, 在研, 主持

2. 呼吸全国重点实验室,自主课题项目,SKLRD-Z-202402,2024-01-01 至 2026-12-31, 在研, 主持

3. 广州医科大学,高层次人才经费项目-科研启动经费,02-412-2302-2172XM,2023-07 至 2028-7


发表论文(部分)

(1)Bingjie Chen; Xianrui Wu; Yongsen Ruan; Yulin Zhang; Qichun Cai; Luis Zapata; Chung-I Wu; Ping Lan; Haijun Wen ; Very large hidden genetic diversity in one single tumor–Evidence for tumors-in-tumor, National Science Review, 2022, 9(12): nwac250 (Research Article,IF=23.18)

(2)Bingjie Chen, Ramazzotti D, Timon Heide, Inmaculada Spiteri; Claire Lynn, Javier Fernandez-Mateos, Chela James, Luca Magnani; Trevor A. Graham; Andrea Sottoriva. Contribution of pks+ E. coli mutations to colorectal carcinogenesis. Nature Communications. 2023 Nov 29;14(1):7827. (Research Article,IF=16.6)

(3)Bingjie Chen; Zongkun Shi; Qingjian Chen; Xu Shen; Darryl Shibata; Haijun Wen; Chung-I Wu; Tumorigenesis as the Paradigm of Quasi-neutral Molecular Evolution, Molecular Biology and    Evolution, 2019, 36(7): 1430-144(Research Article,IF=11.06)

(4)Yongsen Ruan; Haiyu Wang; Bingjie Chen; Haijun Wen; Chung-I Wu ; Mutations Beget More Mutations—Rapid Evolution of Mutation Rate in Response to the Risk of Runaway Accumulation, Molecular Biology and Evolution, 2019, 37(4): 1019   (期刊论文)

(5)Timon Heide; Jacob Househam; George D. Cresswell; Inmaculada Spiteri; Claire Lynn; Maximilian Mossner; Chris Kimberley; Javier Fernandez-Mateos; Bingjie Chen; Luis Zapata; Chela James; Iros Barozzi; Ketevan Chkhaidze; Daniel Nichol; Vinaya Srirangam Nadhamuni; Alison Berner; Melissa Schmidt; Eszter Lakatos; Ann-Marie Baker; Helena Costa; Miriam Mitchinson; Rocco Piazza; Marnix Jansen; Giulio Caravagna; Daniele Ramazzotti; Darryl Shibata; John Bridgewater; Manuel Rodriguez-Justo; Luca Magnani; Trevor A. Graham; Andrea Sottoriva ; The co-evolution of the genome and epigenome in colorectal cancer, Nature, 2022, 611(7937): 733-743   (期刊论文)

(6)Jacob Househam; Timon Heide; George D. Cresswell; Inmaculada Spiteri; Chris Kimberley; Luis Zapata; Claire Lynn; Chela James; Maximilian Mossner; Javier Fernandez-Mateos; Alessandro Vinceti; Ann-Marie Baker; Calum Gabbutt; Alison Berner; Melissa Schmidt; Bingjie Chen; Eszter Lakatos; Vinaya Srirangam Nadhamuni; Daniel Nichol; Helena Costa; Miriam Mitchinson; Daniele Ramazzotti; Benjamin Werner; Francesco Iorio; Marnix Jansen; Giulio Caravagna; Chris P. Barnes; Darryl Shibata; John Bridgewater; Manuel Rodriguez-Justo; Luca Magnani; Andrea Sottoriva; Trevor

A. Graham ; Phenotypic plasticity and genetic control in colorectal cancer evolution, Nature, 2022, 611(7937): 744-753   (期刊论文)

(7)Chung-I Wu; Haijun Wen; Jian Lu; Xiaodong Su; Alice C Hughes; Weiwei Zhai; Chen Chen; Hua Chen; Mingkun Li; Shuhui Song; haohuiQian Z; Qihui Wang; Bingjie Chen; Zixiao Guo; Yongsen Ruan; Xuemei Lu; Fuwen Wei; Li Jin; Le Kang; Yongbiao Xue; Guoping Zhao; Yaping Zhang; On the origin of SARS-CoV-2-The blind watchmaker argument, Science China. Life Sciences, 2021, 64(9): 1560-1563 (期刊论文)